Scientist

Description:

The Scientist will design and synthesize novel chemical constructs as potential new RPT therapies for cancer treatments. The Scientist I/II will be a highly motivated and technically skilled synthetic organic, peptide or medicinal chemist with excellent interpersonal and communication skills. Candidates will work as part of a team of scientists to synthesize and design both small molecules and peptide analogs to optimize potency, pharmacokinetics, and in vivo efficacy of potential drug candidates. The role is highly technical and will need a person who enjoys working at the bench with high productivity and data analysis skills and a comfort level in working under tight timelines.

Job Responsibilities

Essential duties and responsibilities include the following. Other duties may be assigned.
 

• Design and synthesize small molecule/novel peptide compounds in support of SAR campaigns for pipeline projects.
• Contribute towards developing SAR on assigned projects, design and synthesize key target molecules to assess chemical/biological hypothesis.
• Independently plan and execute organic synthesis routes for complex molecules. Utilize modern purification and analytical tools to support synthesis and characterization of target compounds.
• Work in close collaboration with interdisciplinary team members to provide needed chemistry support to guide programs through lead identification/optimization phases.
• Work closely with chemists, DMPK, imaging and in vitro/vivo teams to ensure that target compounds are generated in a timely manner to support the screening funnel.
• Contribute experimental efforts in support of target selection and initiation of new RPT projects.
• Keep abreast of the literature in the field of RPTs, identify novel concepts and ideas to help advance the state of art in RPT field.
• Contribute towards IP filings and drafting of publications, presentations.
• Routinely present research findings, project updates in interdisciplinary team settings.
• Adhere rigorously to safety guidelines, regulatory standards and company policies and ensure a safe working environment.
• Uses AI tools to enhance individual productivity and quality of work
   

Education And Experience
 

• BS 5+ years
• or MS 3+ years
• or PhD 0 years